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Otx2 Promotes the Survival of Damaged Adult Retinal Ganglion Cells and Protects against Excitotoxic Loss of Visual Acuity In Vivo

Retinal ganglion cells (RGCs) are the projection neurons from the eye to the brain and their loss results in visual impairment in a number of diseases. Transcription factors with a homeodomain can translocate between cells and, in at least one reported case, can stimulate neuronal survival. Otx2 is...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ibad, Raoul Torero, Rheey, Jinguen, Mrejen, Sarah, Forster, Valérie, Picaud, Serge, Prochiantz, Alain, Moya, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622718/
https://ncbi.nlm.nih.gov/pubmed/21471386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0187-11.2011
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