Dose-Dependent Nonlinear Effect of l-DOPA on Paired Associative Stimulation-Induced Neuroplasticity in Humans

Dopamine is one of the major neuromodulators in the CNS, which is involved in learning and memory processes. A nonlinear, inverted U-shaped dose–response curve of its effects on cognition has been observed in animal studies. The basis for this nonlinear effect might be a similar effect of dopamine o...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Thirugnanasambandam, Nivethida, Grundey, Jessica, Paulus, Walter, Nitsche, Michael A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622704/
https://ncbi.nlm.nih.gov/pubmed/21471364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6258-10.2011
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