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Structural and evolutionary characteristics of dynamin-related GTPase OPA1

OPA1 is a dynamin-related GTPase that controls mitochondrial fusion, cristae remodeling, energetics and mtDNA maintenance. However, the molecular architecture of OPA1 is poorly understood. Here we modeled the structure of human OPA1 by the threading approach. We found that the C-terminal region of t...

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Pubblicato in:PeerJ
Autori principali: Li, Dandan, Wang, Jinlan, Jin, Zichen, Zhang, Zheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622160/
https://ncbi.nlm.nih.gov/pubmed/31328044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7285
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