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Notch Signaling Controls Generation of Motor Neurons in the Lesioned Spinal Cord of Adult Zebrafish

In mammals, increased Notch signaling is held partly responsible for a lack of neurogenesis after a spinal injury. However, this is difficult to test in an essentially nonregenerating system. We show that in adult zebrafish, which exhibit lesion-induced neurogenesis, e.g., of motor neurons, the Notc...

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Pubblicato in:J Neurosci
Autori principali: Dias, Tatyana B., Yang, Yu-Jie, Ogai, Kazuhiro, Becker, Thomas, Becker, Catherina G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622036/
https://ncbi.nlm.nih.gov/pubmed/22378895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6398-11.2012
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