Influence of DNMT3A R882 mutations on AML prognosis determined by the allele ratio in Chinese patients

BACKGROUND: The influence of DNMT3A R882 mutations on adult acute myeloid leukemia (AML) prognosis is still controversial presently. The influence of R882 allele ratio on drug response and prognosis of AML is unknown yet. Besides, it is obscure whether anthracyclines are involved in chemoresistance...

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Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Yuan, Xiao-Qing, Chen, Peng, Du, Yin-Xiao, Zhu, Ke-Wei, Zhang, Dao-Yu, Yan, Han, Liu, Han, Liu, Yan-Ling, Cao, Shan, Zhou, Gan, Zeng, Hui, Chen, Shu-Ping, Zhao, Xie-Lan, Yang, Jing, Zeng, Wen-Jing, Chen, Xiao-Ping
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621981/
https://ncbi.nlm.nih.gov/pubmed/31291961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1959-3
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