Role of antibiotic use, plasma citrulline and blood microbiome in advanced non-small cell lung cancer patients treated with nivolumab

BACKGROUND: Recent data suggested a role of gut microbiota and antibiotic use on immune checkpoint inhibitors efficacy. We aimed to evaluate the impact of early use of antibiotic (EUA), blood microbiome and plasmatic citrulline (marker of the intestinal barrier) on nivolumab efficacy in non-small ce...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Ouaknine Krief, Julia, Helly de Tauriers, Pierre, Dumenil, Coraline, Neveux, Nathalie, Dumoulin, Jennifer, Giraud, Violaine, Labrune, Sylvie, Tisserand, Julie, Julie, Catherine, Emile, Jean-François, Chinet, Thierry, Giroux Leprieur, Etienne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621972/
https://ncbi.nlm.nih.gov/pubmed/31292005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0658-1
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