The Actin Nucleator Cobl Is Crucial for Purkinje Cell Development and Works in Close Conjunction with the F-Actin Binding Protein Abp1

Cortical actin dynamics shapes cells. To generate actin filaments, cells rely on actin nucleators. Cobl is a novel, brain-enriched, WH2 domain-based actin nucleator, yet, its functions remained largely elusive. Here, we reveal that Cobl plays a crucial role in Purkinje cell development using gene gu...

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Publicado en:J Neurosci
Main Authors: Haag, Natja, Schwintzer, Lukas, Ahuja, Rashmi, Koch, Nicole, Grimm, Julia, Heuer, Heike, Qualmann, Britta, Kessels, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621670/
https://ncbi.nlm.nih.gov/pubmed/23223303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0843-12.2012
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