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Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis
OBJECTIVES: Osteoarthritis (OA) is a painful and debilitating disease and it is associated with aberrant upregulation of multiple factors, including matrix metalloproteinase 13 (MMP13), interleukin-1β (IL-1β) and nerve growth factor (NGF). In this study, we aimed to use the CRISPR/Cas9 technology, a...
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| Vydáno v: | Ann Rheum Dis |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621547/ https://ncbi.nlm.nih.gov/pubmed/30842121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214724 |
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