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Glucocorticoid Suppresses Dendritic Spine Development Mediated by Down-Regulation of Caldesmon Expression

Glucocorticoids (GCs) mediate the effects of stress to cause structural plasticity in brain regions such as the hippocampus, including simplification of dendrites and shrinkage of dendritic spines. However, the molecular mechanics linking stress and GCs to these effects remain largely unclear. Here,...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Tanokashira, Daisuke, Morita, Tsuyoshi, Hayashi, Ken'ichiro, Mayanagi, Taira, Fukumoto, Kentaro, Kubota, Yoshiko, Yamashita, Toshihide, Sobue, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621430/
https://ncbi.nlm.nih.gov/pubmed/23077044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2380-12.2012
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