A New Concept: Aβ(1–42) Generates a Hyperfunctional Proteolytic NCX3 Fragment That Delays Caspase-12 Activation and Neuronal Death

Although the amyloid-β(1–42) (Aβ(1–42)) peptide involved in Alzheimer's disease is known to cause a dysregulation of intracellular Ca(2+) homeostasis, its molecular mechanisms still remain unclear. We report that the extracellular-dependent early increase (30 min) in intracellular calcium conce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pannaccione, Anna, Secondo, Agnese, Molinaro, Pasquale, D'Avanzo, Carla, Cantile, Maria, Esposito, Alba, Boscia, Francesca, Scorziello, Antonella, Sirabella, Rossana, Di Renzo, Gianfranco, Annunziato, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621392/
https://ncbi.nlm.nih.gov/pubmed/22855810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6429-11.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados