Synthesis and Preclinical Evaluation of the Fibrin-Binding Cyclic Peptide (18)F-iCREKA: Comparison with Its Contrasted Linear Peptide

PURPOSE: Cys-Arg-Glu-Lys-Ala (CREKA) is a pentapeptide which can target fibrin-fibronectin complexes. Our previous study has built a probe called iCREKA which was based on CREKA and has proved the feasibility and specificity of iCREKA by the fluorescence experiment. The purpose of this study is to a...

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Dettagli Bibliografici
Pubblicato in:Contrast Media Mol Imaging
Autori principali: Zhang, Yin, Wang, Lijuan, Yu, Sirui, Hu, Kongzhen, Huang, Shun, Li, Youcai, Wu, Hubing, Li, Hongsheng, Wang, Quanshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620859/
https://ncbi.nlm.nih.gov/pubmed/31346326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6315954
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