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Self-assembled insulin and nanogels polyelectrolyte complex (Ins/NGs-PEC) for oral insulin delivery: characterization, lyophilization and in-vivo evaluation

Introduction: Insulin is given by injection, because when administered orally, it would be destroyed by enzymes in the digestive system, hence only about 0.1% reaches blood circulation. The purpose of the present study was to use pH sensitive polyelectrolyte methyl methacrylate (MMA)/itaconic acid (...

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Podrobná bibliografie
Vydáno v:Int J Nanomedicine
Hlavní autoři: Mudassir, Jahanzeb, Darwis, Yusrida, Muhamad, Suriani, Khan, Arshad Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620829/
https://ncbi.nlm.nih.gov/pubmed/31456636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S199507
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