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Glycolysis inhibitors suppress renal interstitial fibrosis via divergent effects on fibroblasts and tubular cells
Renal interstitial fibrosis is a common pathological feature of chronic kidney disease that may involve changes of metabolism in kidney cells. In the present study, we first showed that blockade of glycolysis with either dichloroacetate (DCA) or shikonin to target different glycolytic enzymes reduce...
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| 出版年: | Am J Physiol Renal Physiol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620587/ https://ncbi.nlm.nih.gov/pubmed/30969803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00422.2018 |
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