Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients’ Signatures

By GWAS studies on celiac disease, gene expression was studied at the level of the whole intestinal mucosa, composed by two different compartments: epithelium and lamina propria. Our aim is to analyse the gene-expression and DNA methylation of candidate genes in each of these compartments. Epitheliu...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cielo, D., Galatola, M., Fernandez-Jimenez, N., De Leo, L., Garcia-Etxebarria, K., Loganes, C., Tommasini, A., Not, T., Auricchio, R., Greco, L., Bilbao, J. R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620355/
https://ncbi.nlm.nih.gov/pubmed/31292504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46468-2
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