Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis

Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. To better define th...

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Publicado no:Nat Commun
Main Authors: Penas, Clara, Maloof, Marie E., Stathias, Vasileios, Long, Jun, Tan, Sze Kiat, Mier, Jose, Fang, Yin, Valdes, Camilo, Rodriguez-Blanco, Jezabel, Chiang, Cheng-Ming, Robbins, David J., Liebl, Daniel J., Lee, Jae K., Hatten, Mary E., Clarke, Jennifer, Ayad, Nagi G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620341/
https://ncbi.nlm.nih.gov/pubmed/31292434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10799-5
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