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Disease-causing mutations in subunits of OXPHOS complex I affect certain physical interactions
Mitochondrial complex I (CI) is the largest multi-subunit oxidative phosphorylation (OXPHOS) protein complex. Recent availability of a high-resolution human CI structure, and from two non-human mammals, enabled predicting the impact of mutations on interactions involving each of the 44 CI subunits....
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620328/ https://ncbi.nlm.nih.gov/pubmed/31292494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46446-8 |
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