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Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism

Long intergenic noncoding RNAs (lincRNAs) have emerged as important modulators of cellular functions. Most lincRNAs are not conserved among mammals, raising the fundamental question of whether nonconserved adipose-expressed lincRNAs are functional. To address this, we performed deep RNA sequencing o...

詳細記述

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書誌詳細
出版年:Sci Transl Med
主要な著者: Zhang, Xuan, Xue, Chenyi, Lin, Jennie, Ferguson, Jane F., Weiner, Amber, Liu, Wen, Han, Yumiao, Hinkle, Christine, Li, Wenjun, Jiang, Hongfeng, Gosai, Sager, Hachet, Melanie, Garcia, Benjamin A., Gregory, Brian D., Soccio, Raymond E., Hogenesch, John B., Seale, Patrick, Li, Mingyao, Reilly, Muredach P.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620026/
https://ncbi.nlm.nih.gov/pubmed/29925637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar5987
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