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Prediction of disease-associated mutations in the transmembrane regions of proteins with known 3D structure
Being able to assess the phenotypic effects of mutations is a much required capability in precision medicine. However, most of the currently available structure-based methods actually predict stability changes caused by mutations rather than their pathogenic potential. There are also no dedicated me...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620012/ https://ncbi.nlm.nih.gov/pubmed/31291347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219452 |
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