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Elucidating diversity in the class composition of the minicircle hypervariable region of Trypanosoma cruzi: New perspectives on typing and kDNA inheritance

BACKGROUND: Trypanosoma cruzi, the protozoan causative of Chagas disease, is classified into six main Discrete Typing Units (DTUs): TcI-TcVI. This parasite has around 10(5) copies of the minicircle hypervariable region (mHVR) in their kinetoplastic DNA (kDNA). The genetic diversity of the mHVR is vi...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Rusman, Fanny, Tomasini, Nicolás, Yapur, Noelia-Floridia, Puebla, Andrea F., Ragone, Paula G., Diosque, Patricio
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619836/
https://ncbi.nlm.nih.gov/pubmed/31247047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007536
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