Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures

Some neurodegenerative diseases, like Parkinsons Disease (PD) and Spinocerebellar ataxia 3 (SCA3), are associated with distinct, altered gait and tremor movements that are reflective of the underlying disease etiology. Drosophila melanogaster models of neurodegeneration have illuminated our understa...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Wu, Shuang, Tan, Kah Junn, Govindarajan, Lakshmi Narasimhan, Stewart, James Charles, Gu, Lin, Ho, Joses Wei Hao, Katarya, Malvika, Wong, Boon Hui, Tan, Eng-King, Li, Daiqin, Claridge-Chang, Adam, Libedinsky, Camilo, Cheng, Li, Aw, Sherry Shiying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619818/
https://ncbi.nlm.nih.gov/pubmed/31246996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000346
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