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Characterization of Serotonin Signaling Components in Patients with Inflammatory Bowel Disease
BACKGROUND: Tryptophan hydroxylase (TPH)1 catalyzes the biosynthesis of serotonin (5-hydroxytrptamine; 5-HT) in enterochromaffin (EC) cells, the predominant source of gut 5-HT. Secreted 5-HT regulates various gut functions through diverse 5-HT receptor (5-HTR) families, and 5-HT transporter (5-HTT)...
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| Publicado no: | J Can Assoc Gastroenterol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6619411/ https://ncbi.nlm.nih.gov/pubmed/31294376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy039 |
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