Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury

Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins. We investigated the role of Nrf2 in intravascular hemoly...

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Publicat a:Front Pharmacol
Autors principals: Rubio-Navarro, Alfonso, Vázquez-Carballo, Cristina, Guerrero-Hue, Melania, García-Caballero, Cristina, Herencia, Carmen, Gutiérrez, Eduardo, Yuste, Claudia, Sevillano, Ángel, Praga, Manuel, Egea, Javier, Cannata, Pablo, Cortegano, Isabel, de Andrés, Belén, Gaspar, María Luisa, Cadenas, Susana, Michalska, Patrycja, León, Rafael, Ortiz, Alberto, Egido, Jesús, Moreno, Juan Antonio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619398/
https://ncbi.nlm.nih.gov/pubmed/31333462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00740
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