The Neuronal Serum- and Glucocorticoid-Regulated Kinase 1.1 Reduces Neuronal Excitability and Protects against Seizures through Upregulation of the M-Current

The M-current formed by tetramerization of Kv7.2 and Kv7.3 subunits is a neuronal voltage-gated K(+) conductance that controls resting membrane potential and cell excitability. In Xenopus laevis oocytes, an increase in Kv7.2/3 function by the serum- and glucocorticoid-regulated kinase 1 (SGK1) has b...

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Udgivet i:J Neurosci
Main Authors: Miranda, Pablo, Cadaveira-Mosquera, Alba, González-Montelongo, Rafaela, Villarroel, Alvaro, González-Hernández, Tomás, Lamas, J. Antonio, Alvarez de la Rosa, Diego, Giraldez, Teresa
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619182/
https://ncbi.nlm.nih.gov/pubmed/23392695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3442-12.2013
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