Induction of Thermal Hyperalgesia and Synaptic Long-Term Potentiation in the Spinal Cord Lamina I by TNF-α and IL-1β is Mediated by Glial Cells

Long-term potentiation (LTP) of synaptic strength in nociceptive pathways is a cellular model of hyperalgesia. The emerging literature suggests a role for cytokines released by spinal glial cells for both LTP and hyperalgesia. However, the underlying mechanisms are still not fully understood. In rat...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Gruber-Schoffnegger, Doris, Drdla-Schutting, Ruth, Hönigsperger, Christoph, Wunderbaldinger, Gabriele, Gassner, Matthias, Sandkühler, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619063/
https://ncbi.nlm.nih.gov/pubmed/23575851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5087-12.2013
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