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Mutation of Foxo3 Causes Adult Onset Auditory Neuropathy and Alters Cochlear Synapse Architecture in Mice

Auditory neuropathy is a form of hearing loss in which cochlear inner hair cells fail to correctly encode or transmit acoustic information to the brain. Few genes have been implicated in the adult-onset form of this disease. Here we show that mice lacking the transcription factor Foxo3 have adult on...

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Pubblicato in:J Neurosci
Autori principali: Gilels, Felicia, Paquette, Stephen T., Zhang, Jingyuan, Rahman, Irfan, White, Patricia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618809/
https://ncbi.nlm.nih.gov/pubmed/24259566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2529-13.2013
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