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Enantioselective Catalytic [4+1]‐Cyclization of ortho‐Hydroxy‐para‐Quinone Methides with Allenoates

The first highly asymmetric catalytic synthesis of densely functionalized dihydrobenzofurans is reported, which starts from ortho‐hydroxy‐containing para‐quinone methides. The reaction relies on an unprecedented formal [4+1]‐annulation of these quinone methides with allenoates in the presence of a c...

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Publicat a:Chemistry
Autors principals: Zielke, Katharina, Kováč, Ondřej, Winter, Michael, Pospíšil, Jiří, Waser, Mario
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618147/
https://ncbi.nlm.nih.gov/pubmed/31020717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201901784
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