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Sustained‐release of sclerostin single‐chain antibody fragments using poly(lactic‐co‐glycolic acid) microspheres for osteoporotic fracture repair

Osteoporotic fracture is one of the most common bone diseases in middle and old age, as the most serious consequence of osteoporosis. Sclerostin single‐chain antibody fragments (SCL‐scFv) have been proven to promote bone formation by binding to scleroprotein, a natural antagonist of the Wnt pathway,...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Li, Ming, Li, Shifei, Liu, Jianheng, Cui, Xiang, Zhang, Shudong, Zhou, Jian, Wang, Xiumei, Yao, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618085/
https://ncbi.nlm.nih.gov/pubmed/31012249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36704
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