Mechanism of trastuzumab resistance caused by HER-2 mutation in breast carcinomas

Background: Trastuzumab is an effective drug for the treatment of Her2-positive breast cancer. But, primary or secondary resistances to trastuzumab have become an important factor influencing the curative effect. The mechanisms of trastuzumab resistance are somewhat complex. The present work aims to...

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Publicat a:Cancer Manag Res
Autors principals: Kong, Xiangyi, Zhang, Kai, Wang, Xiangyu, Yang, Xue, Li, Yalun, Zhai, Jie, Xing, Zeyu, Qi, Yihang, Gao, Ran, Feng, Xiaoli, Wang, Jing, Fang, Yi
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618040/
https://ncbi.nlm.nih.gov/pubmed/31308740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S194137
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