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Distinct chromatin structures at the monoamine oxidase‐A promoter correlate with allele‐specific expression in SH‐SY5Y cells

Monoamine oxidase‐A (MAOA) metabolises monoamines and is implicated in the pathophysiology of psychiatric disorders. A polymorphic repetitive DNA domain, termed the uVNTR (upstream variable number tandem repeat), located at the promoter of the MAOA gene is a risk factor for many of these disorders....

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Bibliographische Detailangaben
Veröffentlicht in:Genes Brain Behav
Hauptverfasser: Manca, M., Pessoa, V., Myers, P., Pickles, A., Hill, J., Sharp, H., Murgatroyd, C., Bubb, V. J., Quinn, J. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617726/
https://ncbi.nlm.nih.gov/pubmed/29667298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12483
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