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Pathological changes are associated with shifts in the employment of synonymous codons at the transcriptome level
BACKGROUND: The usage of different synonymous codons reflects the genome organization and has been connected to parameters such as mRNA abundance and protein folding. It is also been established that mutations targeting specific synonymous codons can trigger disease. RESULTS: We performed a systemat...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6617700/ https://ncbi.nlm.nih.gov/pubmed/31288782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5921-9 |
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