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Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus

BACKGROUND: Hypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals. However, the effect of chronic HFD feeding on oligodendrocytes (OLGs), a myelin-producing glial population in the central nervous...

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Dades bibliogràfiques
Publicat a:BMC Neurosci
Autors principals: Huang, Hui-Ting, Tsai, Sheng-Feng, Wu, Hung-Tsung, Huang, Hsin-Ying, Hsieh, Han-Hsueh, Kuo, Yu-Ming, Chen, Po-See, Yang, Chung-Shi, Tzeng, Shun-Fen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617565/
https://ncbi.nlm.nih.gov/pubmed/31291887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-019-0516-6
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