The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development

Malaria represents a major cause of death from infectious disease. Hemozoin is a Plasmodium-derived product that contributes to progression of cerebral malaria. However, there is a gap of knowledge regarding how hemozoin is recognized by innate immunity. Myeloid C-type lectin receptors (CLRs) encomp...

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Pubblicato in:Cell Rep
Autori principali: Raulf, Marie-Kristin, Johannssen, Timo, Matthiesen, Svea, Neumann, Konstantin, Hachenberg, Severin, Mayer-Lambertz, Sabine, Steinbeis, Fridolin, Hegermann, Jan, Seeberger, Peter H., Baumgärtner, Wolfgang, Strube, Christina, Ruland, Jürgen, Lepenies, Bernd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616648/
https://ncbi.nlm.nih.gov/pubmed/31269448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.015
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