Macrophages Down-Regulate Gene Expression of Intervertebral Disc Degenerative Markers Under a Pro-inflammatory Microenvironment

Low back pain is a highly prevalent clinical problem and intervertebral disc (IVD) degeneration is now accepted as the major pathophysiological mechanism responsible for this condition. Accumulating evidence suggests that inflammation plays a crucial role in the progression of human IVD degeneration...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Silva, Ana J., Ferreira, Joana R., Cunha, Carla, Corte-Real, João V., Bessa-Gonçalves, Mafalda, Barbosa, Mario A., Santos, Susana G., Gonçalves, Raquel M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616110/
https://ncbi.nlm.nih.gov/pubmed/31333653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01508
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