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Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells

The conserved oligomeric complex (COG) is a multi-subunit vesicle tethering complex that functions in retrograde trafficking at the Golgi. We have previously demonstrated that the formation of enlarged endo-lysosomal structures (EELSs) is one of the major glycosylation-independent phenotypes of cell...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: D’Souza, Zinia, Blackburn, Jessica Bailey, Kudlyk, Tetyana, Pokrovskaya, Irina D., Lupashin, Vladimir V.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616090/
https://ncbi.nlm.nih.gov/pubmed/31334232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00118
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