Simultaneously inhibiting undecaprenyl phosphate production and peptidoglycan synthases promotes rapid lysis in Escherichia coli

Peptidoglycan (PG) is a highly cross-linked polysaccharide that encases bacteria, resists the effects of turgor and confers cell shape. PG precursors are translocated across the cytoplasmic membrane by the lipid carrier undecaprenyl phosphate (Und-P) where they are incorporated into the PG superstru...

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Veröffentlicht in:Mol Microbiol
Hauptverfasser: Jorgenson, Matthew A., MacCain, William J., Meberg, Bernadette M., Kannan, Suresh, Bryant, Joseph C., Young, Kevin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616000/
https://ncbi.nlm.nih.gov/pubmed/31022322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14265
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