Identifying, understanding, and correcting technical artifacts on the sex chromosomes in next-generation sequencing data

BACKGROUND: Mammalian X and Y chromosomes share a common evolutionary origin and retain regions of high sequence similarity. Similar sequence content can confound the mapping of short next-generation sequencing reads to a reference genome. It is therefore possible that the presence of both sex chrom...

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Detalles Bibliográficos
Publicado en:Gigascience
Main Authors: Webster, Timothy H, Couse, Madeline, Grande, Bruno M, Karlins, Eric, Phung, Tanya N, Richmond, Phillip A, Whitford, Whitney, Wilson, Melissa A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Technical Note
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615978/
https://ncbi.nlm.nih.gov/pubmed/31289836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giz074
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