Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial

INTRODUCTION: Regenerative medicine and cell therapies have been gaining much attention among clinicians. Therapeutic infusion of mesenchymal stromal cells (MSCs) is now a leading investigational strategy for the treatment of acute graft-versus-host disease (aGVHD). Bone marrow MSCs are approved for...

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Veröffentlicht in:BMJ Open
Hauptverfasser: Yamahara, Kenichi, Hamada, Akiko, Soma, Toshihiro, Okamoto, Rika, Okada, Masaya, Yoshihara, Satoshi, Yoshihara, Kyoko, Ikegame, Kazuhiro, Tamaki, Hiroya, Kaida, Katsuji, Inoue, Takayuki, Ohsugi, Yuko, Nishikawa, Hiroki, Hayashi, Hiroshi, Ito, Yoichi M, Iijima, Hiroaki, Ohnishi, Shunsuke, Hashimoto, Daigo, Isoe, Toshiyuki, Teshima, Takanori, Ogawa, Hiroyasu, Sato, Norihiro, Fujimori, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Haematology (Incl Blood Transfusion)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615811/
https://ncbi.nlm.nih.gov/pubmed/31289066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-026403
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