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The Ca-loop in thymidylate kinase is critical for growth and contributes to pyrimidine drug sensitivity of Candida albicans
The yeast Candida albicans is the most prevalent opportunistic fungal pathogen in humans. Drug resistance among C. albicans isolates poses a common challenge, and overcoming this resistance represents an unmet need in managing this common pathogen. Here, we investigated CDC8, encoding thymidylate ki...
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Pubblicato in: | J Biol Chem |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615673/ https://ncbi.nlm.nih.gov/pubmed/31152062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006798 |
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