High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation

BACKGROUND: By post-transcriptionally regulating multiple target transcripts, microRNAs (miRNAs or miR) play important biological functions. H1 embryonic stem cells (hESCs) and NTera-2 embryonal carcinoma cells (ECCs) are two of the most widely used human pluripotent model cell lines, sharing severa...

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Foilsithe in:Stem Cell Res Ther
Main Authors: de Souza Lima, Ildercílio Mota, Schiavinato, Josiane Lilian dos Santos, Paulino Leite, Sarah Blima, Sastre, Danuta, Bezerra, Hudson Lenormando de Oliveira, Sangiorgi, Bruno, Corveloni, Amanda Cristina, Thomé, Carolina Hassibe, Faça, Vitor Marcel, Covas, Dimas Tadeu, Zago, Marco Antônio, Giacca, Mauro, Mano, Miguel, Panepucci, Rodrigo Alexandre
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615276/
https://ncbi.nlm.nih.gov/pubmed/31287022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1318-6
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