Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway

Inflammation is a crucial component of various stress-induced responses that contributes to the pathogenesis of major depressive disorder (MDD). Depressive-like behavior (DLB) is characterized by decreased mobility and depressive behavior that occurs in systemic infection induced by Lipopolysacchari...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Arioz, Burak I., Tastan, Bora, Tarakcioglu, Emre, Tufekci, Kemal Ugur, Olcum, Melis, Ersoy, Nevin, Bagriyanik, Alper, Genc, Kursad, Genc, Sermin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615259/
https://ncbi.nlm.nih.gov/pubmed/31327964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01511
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