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Homolog-Dependent Repair Following Dicentric Chromosome Breakage in Drosophila melanogaster

Double-strand DNA breaks are repaired by one of several mechanisms that rejoin two broken ends. However, cells are challenged when asked to repair a single broken end and respond by: (1) inducing programmed cell death; (2) healing the broken end by constructing a new telomere; (3) adapting to the br...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Bhandari, Jayaram, Karg, Travis, Golic, Kent G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614899/
https://ncbi.nlm.nih.gov/pubmed/31053594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302247
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