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Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing

Chromatin organization and epigenetic markers influence splicing, though the magnitudes of these effects and the mechanisms are largely unknown. Here, we demonstrate that linker histone H1.5 influences mRNA splicing. We observed that linker histone H1.5 binds DNA over splice sites of short exons in...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Glaich, Ohad, Leader, Yodfat, Lev Maor, Galit, Ast, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614845/
https://ncbi.nlm.nih.gov/pubmed/31076740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz338
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