Pattern preferences of DNA nucleotide motifs by polyamines putrescine(2+), spermidine(3+) and spermine(4+)

The interactions of natural polyamines (putrescine(2+), spermidine(3+) and spermine(4+)) with DNA double helix are studied to characterize their nucleotide sequence pattern preference. Atomistic Molecular Dynamics simulations have been carried out for three systems consisting of the same DNA fragmen...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Perepelytsya, Sergiy, Uličný, Jozef, Laaksonen, Aatto, Mocci, Francesca
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Computational Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614828/
https://ncbi.nlm.nih.gov/pubmed/31114917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz434
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