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Feasability of Introducing a Thioether Ring in Vasopressin by nisBTC Co-expression in Lactococcus lactis

Introducing one or more intramolecular thioether bridges in a peptide provides a promising approach to create more stable molecules with improved pharmacodynamic properties and especially to protect peptides against proteolytic degradation. Lanthipeptides are compounds that naturally possess thioeth...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Li, Qian, Montalban-Lopez, Manuel, Kuipers, Oscar P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614560/
https://ncbi.nlm.nih.gov/pubmed/31333616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01508
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