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Differences in placental capillary shear stress in fetal growth restriction may affect endothelial cell function and vascular network formation

Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but the mechanisms driving this are poorly understood. We hypothesize that vascular structural malformation at the o...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tun, Win M., Yap, Choon Hwai, Saw, Shier Nee, James, Joanna L., Clark, Alys R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614400/
https://ncbi.nlm.nih.gov/pubmed/31285454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46151-6
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