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Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer

BACKGROUND: Ductal adenocarcinoma of the prostate is an aggressive subtype, with high rates of biochemical recurrence and overall poor prognosis. It is frequently found coincident with conventional acinar adenocarcinoma. The genomic features driving evolution to its ductal histology and the biology...

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Detalhes bibliográficos
Publicado no:Eur Urol Focus
Main Authors: Gillard, Marc, Lack, Justin, Pontier, Andrea, Gandla, Divya, Hatcher, David, Sowalsky, Adam G., Rodriguez-Nieves, Jose, Vander Griend, Donald, Paner, Gladell, VanderWeele, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614018/
https://ncbi.nlm.nih.gov/pubmed/29229583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euf.2017.12.003
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