The MTOR signaling pathway regulates macrophage differentiation from mouse myeloid progenitors by inhibiting autophagy

Understanding of the mechanism for myeloid differentiation provides important insights into the hematopoietic developmental processes. By using an ESC-derived myeloid progenitor cell model, we found that CSF2/GM-CSF triggered macrophage differentiation and activation of the MTOR signaling pathway. A...

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Detalles Bibliográficos
Publicado en:Autophagy
Main Authors: Zhang, Meichao, Liu, Furao, Zhou, Pingting, Wang, Qian, Xu, Ci, Li, Yanyan, Bian, Lei, Liu, Yuanhua, Zhou, Jiaxi, Wang, Fei, Yao, Yuan, Fang, Yong, Li, Dong
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Research Paper - Basic Science
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613836/
https://ncbi.nlm.nih.gov/pubmed/30724690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1578040
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