The MTOR signaling pathway regulates macrophage differentiation from mouse myeloid progenitors by inhibiting autophagy

Understanding of the mechanism for myeloid differentiation provides important insights into the hematopoietic developmental processes. By using an ESC-derived myeloid progenitor cell model, we found that CSF2/GM-CSF triggered macrophage differentiation and activation of the MTOR signaling pathway. A...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Meichao, Liu, Furao, Zhou, Pingting, Wang, Qian, Xu, Ci, Li, Yanyan, Bian, Lei, Liu, Yuanhua, Zhou, Jiaxi, Wang, Fei, Yao, Yuan, Fang, Yong, Li, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613836/
https://ncbi.nlm.nih.gov/pubmed/30724690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1578040
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