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Childhood asthma inception and progression: role of microbial exposures, susceptibility to viruses and early allergic sensitization

Inappropriate responses to respiratory viruses, especially rhinovirus, and early allergic sensitization are the strongest contributors to the inception and persistence of early onset asthma. The ORMDL3 asthma locus in chromosome 17q seems to exert its effects by increasing susceptibility to HRV in e...

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Pubblicato in:Immunol Allergy Clin North Am
Autore principale: Martinez, Fernando D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613822/
https://ncbi.nlm.nih.gov/pubmed/30954166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.iac.2018.12.001
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