Unbiased screen of RNA tailing activities reveals a poly(UG) polymerase

Ribonucleotidyl transferases (rNTases) add non-templated ribonucleotides to diverse RNAs. We developed TRAID-Seq, a screening strategy in S. cerevisiae to identify sequences added to a reporter RNA at single-nucleotide resolution by overexpressing candidate enzymes from different organisms. The rNTa...

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Bibliografiska uppgifter
I publikationen:Nat Methods
Huvudupphovsmän: Preston, Melanie A., Porter, Douglas F., Chen, Fan, Buter, Natascha, Lapointe, Christopher P., Keles, Sunduz, Kimble, Judith, Wickens, Marvin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613791/
https://ncbi.nlm.nih.gov/pubmed/30988468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0370-6
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