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Therapeutic Targeting of Notch Signaling Pathway in Hematological Malignancies

The Notch pathway plays a key role in several processes, including stem-cell self-renewal, proliferation, and cell differentiation. Several studies identified recurrent mutations in hematological malignancies making Notch one of the most desirable targets in leukemia and lymphoma. The Notch signalin...

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Podrobná bibliografie
Vydáno v:Mediterr J Hematol Infect Dis
Hlavní autoři: Sorrentino, Claudia, Cuneo, Antonio, Roti, Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: Università Cattolica del Sacro Cuore 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613627/
https://ncbi.nlm.nih.gov/pubmed/31308913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2019.037
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